Bio-Connect

Anti-CD21 [THB-5]

Ab01121-10.0
Absolute Antibody
ApplicationsFlow Cytometry, ImmunoFluorescence
Product group Antibodies
TargetCR2
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD21 [THB-5]
  • Delivery Days Customer
    7
  • Application Supplier Note
    The binding specificity of this antibody has been confirmed in flow cytometry and immunofluorescence analysis (Tedder et al, 1984), with only B cell reactivity observed. Though this antibody binds to CD21, which acts as a receptor for Epstein-Barr virus (EBV), it cannot alone block viral entry into B cells (Fingeroth et al, 1984). EBV virions engineered to express this antibody at their surface have been used to probe the need for CD21 binding to achieve viral entry (Busse et al, 2010).
  • Applications
    Flow Cytometry, ImmunoFluorescence
  • Applications Supplier
    IF; FC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    THB-5
  • Gene ID1380
  • Target name
    CR2
  • Target description
    complement C3d receptor 2
  • Target synonyms
    C3DR; CD21; complement component (3d/Epstein Barr virus) receptor 2; complement component 3d receptor 2; complement receptor type 2; CR; CVID7; EBV receptor; SLEB9
  • Host
    Human
  • Isotype
    IgG1
  • Protein IDP20023
  • Protein Name
    Complement receptor type 2
  • Scientific Description
    This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    This antibody was raised by immunising BALB/c mice with human B cells of the SB line. Spleen cells were then removed and fused with Ag8.653 myeloma cells, to produce stable hybridomas.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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