anti-CD252 [OX40L] (human), mAb (ANC10G1) (R-PE)

Ancell Corporation

anti-CD252 [OX40L] (human), mAb (ANC10G1) (R-PE)

10

Flow Cytometry, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

ANC10G1

RPE

Mouse

IgG1

Human CD252 (CD134L; OX40 ligand) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD252 binds to CD134 (OX40) present on activated T cells, providing a costimulatory signal. Blockade of this interaction in mouse abrogated immunological effects in several models of inflammation and rejection. - Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC10G1. Applications: ELISA, FACS, FUNC (Blocking). 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Human CD252 (CD134L; OX40 ligand) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD252 binds to CD134 (OX40) present on activated T cells, providing a costimulatory signal. Blockade of this interaction in mouse abrogated immunological effects in several models of inflammation and rejection.

Human

2°C to 8°C

12352203