anti-CD275 [B7-H2] (human), mAb (ANC4E3) (Biotin)
ANC-263-030
ApplicationsELISA
Product group Antibodies
ReactivityHuman
Overview
- SupplierAncell Corporation
- Product Nameanti-CD275 [B7-H2] (human), mAb (ANC4E3) (Biotin)
- Delivery Days Customer10
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDANC4E3
- ConjugateBiotin
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMonoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC4E3. Applications: ELISA. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE. - The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203