anti-CD279 [PD-1] (human), mAb (ANC4H6) (preservative free)

Ancell Corporation

anti-CD279 [PD-1] (human), mAb (ANC4H6) (preservative free)

10

Flow Cytometry, ELISA

Research Use Only

Monoclonal

ANC4H6

Liquid

Mouse

IgG1

Human CD279 (PD-1; Programmed Death 1) is a 55kDa Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses. - Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC4H6. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl Human CD279 (PD-1; Programmed Death 1) is a 55kDa Ig superfamily member with similarity to CD28 and CD152 (CTLA-4). It is expressed on activated T and B and myeloid cells and engagement by its ligands PD-L1 (CD274; B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti-cancer responses.

Human

2°C to 8°C

12352203