Anti-CD31 Antibody [7-A1]

HUABIO

Anti-CD31 Antibody [7-A1]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

WB,IF-Cell,IF-Tissue,IHC-P,FC

Research Use Only

Monoclonal

7-A1

2 mg/ml

Unconjugated

PECAM1

platelet and endothelial cell adhesion molecule 1

CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM, platelet endothelial cell adhesion molecule, CD31 antigen, platelet endothelial cell adhesion molecule-1

Mouse

IgG2a

Platelet endothelial cell adhesion molecule

Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms tumors, Ewings sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmanns syndrome, anosmia with secondary hypogonadism.

Human

Human

-20°C,2°C to 8°C

41116161