Anti-CD34 Antibody [15H1]

HUABIO

Anti-CD34 Antibody [15H1]

7

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

IHC-P,FC

Research Use Only

Monoclonal

15H1

2 mg/ml

Unconjugated

CD34

CD34 molecule

hematopoietic progenitor cell antigen CD34, CD34 antigen, CD34 sialomucin

Mouse

IgG1

CD34 antigen isoform 2

Both isoforms are expressed on the cell surface. CD34-T/CD34-F ratio increases with cell differentiation,developmental stage:On early hematopoietic progenitor cells.,disease:Abnormal CD34 expression in leukemogenesis.,function:Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.,online information:CD34 entry,PTM:Highly glycosylated.,PTM:Phosphorylated on serine residues by PKC.,similarity:Belongs to the CD34 family.,tissue specificity:Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.,

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161