anti-CD357 [GITR] (human), mAb (ANC5E3) (Biotin)
ANC-368-030
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman
Overview
- SupplierAncell Corporation
- Product Nameanti-CD357 [GITR] (human), mAb (ANC5E3) (Biotin)
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDANC5E3
- ConjugateBiotin
- HostMouse
- IsotypeIgG3
- Scientific DescriptionGlucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation. - Monoclonal Antibody. Isotype: Mouse IgG3kappa. Clone: ANC5E3. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203