Anti-CD41 Mouse mAb

PTM BIO

Anti-CD41 Mouse mAb

5

Flow Cytometry

FC

Research Use Only

Monoclonal

10599

Unconjugated

Mouse

IgG

Integrin alpha-IIb

CD41, also named as integrin alfa-IIb/bèta-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bondconnected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203