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anti-CD45RO (human), mAb (UCHL1) (preservative free)

Research Use Only
ANC-194-820
Ancell Corporation
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Primate
Price on request
Packing Size
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Overview

  • Supplier
    Ancell Corporation
  • Product Name
    anti-CD45RO (human), mAb (UCHL1) (preservative free)
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    UCHL1
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RO isoform contains none of the alternatively spliced exons and is present on most thymocytes, a subpopulation of resting (memory) T cells within both CD4 and CD8 subsets as well as on monocytes and granulocytes. CD45RO plays an essential role in lymphocyte activation. - Monoclonal Antibody. Isotype: Mouse IgG2a. Clone: UCHL1. Applications: FACS. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RO isoform contains none of the alternatively spliced exons and is present on most thymocytes, a subpopulation of resting (memory) T cells within both CD4 and CD8 subsets as well as on monocytes and granulocytes. CD45RO plays an essential role in lymphocyte activation.
  • Reactivity
    Human, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203