Anti-CD48 [OX-78]

Absolute Antibody

Anti-CD48 [OX-78]

7

OX-78 binds specifically to CD48 targets and labels mouse thymocytes, B and T cells and macrophages. CD48 is a CD2 ligand and may be involved in the facilitation of interactions between activated lymphocytes. This protein is also likely to be involved in

This antibody binds CD48, and has been used in immunoprecipitation and blocking studies to identify and characterise CD48, the ligand for murine CD2 (Kato, 1992). This antibody is able to block the binding of a chimeric molecule comprised of the extracellular domain of mouse CD2 and human IgG1 Fc to T cell lines at the ligand site.

Flow Cytometry, ImmunoPrecipitation, Neutralisation/Blocking

FC; IP; block

Research Use Only

Monoclonal

OX-78

Cd48

CD48 antigen

AI449234; AW610730; BCM1; Bcm-1; BCM1 surface antigen; BLAS; BLAST; BLAST1; BLAST-1; CD48 antigen; HM48-1; MEM-102; MRC OX-45 surface antigen; Sgp-; Sgp-60; signaling lymphocytic activation molecule 2; SLAM family member 2; SLAMF2

Mouse

IgG2a

CD48 antigen

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Mouse

Mouse

OX-78 was prepared by immunising rats against mouse CD48.

-20°C,2°C to 8°C

12352203