Anti-CD49F [GoH3]

Absolute Antibody

Anti-CD49F [GoH3]

7

This antibody is specific for the mouse, human and dog version of the CD49F protein. CD49F is a receptor for laminin on platelets. Furthermore CD49F is present in oocytes and is involved in sperm-egg fusion.

To determine the influence of anti-CD49f and anti-CD29 monoclonal antibodies on mitotic activity of epithelial cells, cryo-sections of human cultured gingiva were stained for immunohistochemistry using the mouse version of this antibody. (Becker et al, 2002; pmid:12013557). To isolate pancreatic islet progenitor cells from foetal mice, a mouse pancreatic cell dispersion was used for flow cytometry using the mouse version of this antibody (Sugiyama et al, 2006; pmid:17190805). To present evidence that HPV binds specifically to laminin 5, cultured keratinocytes infected with VLPs from HPV-11, were stained using the mouse version of this antibody (Culp et al, 2006; pmid:16940506).

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry

IHC; FC; IF

Research Use Only

Monoclonal

GoH3

ITGA6

integrin subunit alpha 6

CD49 antigen-like family member F; CD49f; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6B; VLA-6

Human

IgG1

Integrin alpha-6

This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2a format for improved compatibility with existing reagents assays and techniques.

Canine, Human, Mouse

Dog, Human, Mouse

This antibody was raised by immunizing a BALB/c rat with amino acids 1242-1255 of the C-terminus of the Human c-erbB-2/HER-2/neu protein

-20°C,2°C to 8°C

12352203