Anti-CD53 [OX-44]

Absolute Antibody

Anti-CD53 [OX-44]

9

This antibody binds rat CD53, and consequently labels all myeloid cells and peripheral lymphoid cells, but only 12% of thymocytes (Paterson, 1987). Functional studies indicate that this subset of OX-44+ thymic cells includes all thymocytes that are on the pathway to immunocompetent T lymphocytes. By contrast, the OX-44- compartment represents cells that are negative for proliferation and thymopoiesic activity, and are fated to die in situ. In addition, this antibody has been used in conjunction with CD4 and CD8 antigens to define seven subsets of thymic cell. Most CD4-CD8- cells are OX-44+, whereas almost all CD4+ CD8+ cells were OX-44-

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

OX-44

Cd53

Cd53 molecule

OX44, Ox-44, leukocyte surface antigen CD53, CD53 antigen, cell surface glycoprotein CD53, leukocyte antigen MRC OX-44

Mouse

IgG1

Leukocyte surface antigen CD53

Rat

-20°C,2°C to 8°C

12352203