Anti-CD55 Antibody [12F1]

HUABIO

Anti-CD55 Antibody [12F1]

7

Flow Cytometry, Western Blot

WB,FC

Research Use Only

Monoclonal

12F1

2 mg/ml

Unconjugated

CD55

CD55 molecule (Cromer blood group)

CHAPLE, CR, CROM, DAF, TC, complement decay-accelerating factor, CD55 antigen, CD55 molecule, decay accelerating factor for complement (Cromer blood group), Cromer blood group antigen, Rh blood group D antigen

Mouse

IgG1

Complement decay-accelerating factor

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade . Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage .

Human

Human

-20°C,2°C to 8°C

41116161