Anti-CD55 [LU30]
Ab00476-23.0
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCD55
Overview
- SupplierAbsolute Antibody
- Product NameAnti-CD55 [LU30]
- Delivery Days Customer7
- Antibody SpecificityThe antibody binds to CD55 with a Kd of 13 nM.
- Application Supplier NoteThe antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- Applications SupplierELISA; IHC; WB
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDLU30
- Gene ID1604
- Target nameCD55
- Target descriptionCD55 molecule (Cromer blood group)
- Target synonymsCD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CHAPLE; complement decay-accelerating factor; CR; CROM; Cromer blood group antigen; DAF; Rh blood group D antigen; TC
- HostRabbit
- IsotypeIgG
- Protein IDP08174
- Protein NameComplement decay-accelerating factor
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteHuman CD55.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203