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Immunohistochemical staining of formalin fixed and paraffin embedded human brain tissue section using anti-CD56 rabbit monoclonal antibody (Clone RM315) at a 1:1000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human brain tissue section using anti-CD56 rabbit monoclonal antibody (Clone RM315) at a 1:1000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human brain tissue section using anti-CD56 rabbit monoclonal antibody (Clone RM315) at a 1:1000 dilution.

anti-CD56 (human), Rabbit Monoclonal (RM315)

Research Use Only
REV-31-1201-00
RevMAb Biosciences
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNCAM1
Price on request
Packing Size
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Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-CD56 (human), Rabbit Monoclonal (RM315)
  • Delivery Days Customer
    5
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM315
  • Gene ID4684
  • Target name
    NCAM1
  • Target description
    neural cell adhesion molecule 1
  • Target synonyms
    antigen recognized by monoclonal antibody 5.1H11; CD56; MSK39; NCAM; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    CD56 (NCAM; Neural Cell Adhesion Molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms. - Recombinant Antibody. This antibody reacts to human CD56 (NCAM1). It may also react to mouse CD56, as predicted by immunogen homology. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD56 (NCAM; Neural Cell Adhesion Molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203