Anti-CD6 [OX-52]

Absolute Antibody

Anti-CD6 [OX-52]

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This antibody is specific for rat CD6, which is largely restricted to cells of the T-lymphocyte lineage.

This antibody recognizes rat CD6, which is largely restricted to cells of the T-lymphocyte lineage, and, as a result, this antibody can be used to identify such cells in tissues or cell suspensions (Robinson, 1986). In cell suspensions prepared from lymph node, TDL, thymus and spleen, exclusively T cells are labelled. Using the immunoperoxidase technique on cryostat tissue sections, staining is mainly confined to the T-cell areas of the spleen, lymph nodes and Peyers patches, as well as all thymocytes. However, occassional positive cells have been observed in the B cell areas of lymphoid organs (Robinson, 1986), and consequently this antibody is used in conjunction with other markers, such as OX-19, to identify T cells.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

FC; IHC-fr; IP

Research Use Only

Monoclonal

OX-52

Cd6

Cd6 molecule

CD6 antigen, Tp120; OX52; T-cell differentiation antigen CD6; T-cell differentiation antigen CD6-like

Mouse

IgG2a

CD6 antigen

Rat

Rat

This antibody was prepared by immunizing BALB/c mice intraperitoneally with 4x10^7 rat (PVG-RT1c) thoracic duct leucocytes, followed 10 days later by a second injection of 4x 10^7 PVG-RT1c spleen cells.

-20°C,2°C to 8°C

12352203