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ProductsBack/anti-CD66b (human), mAb (ANC1D5) (preservative free)

anti-CD66b (human), mAb (ANC1D5) (preservative free)

Research Use Only
ANC-217-820
Ancell Corporation
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman
TargetCEACAM8
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Overview

  • Supplier
    Ancell Corporation
  • Product Name
    anti-CD66b (human), mAb (ANC1D5) (preservative free)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Binds to CD66b on the cell surface of human PMN in flow cytometry and detects recombinant human CD66b in sandwich EIA utilizing either clone ANC4A4(Cat #ANC-220-020) or ANC3C5(Cat# ANC-219-020) as a capture reagent. May cross-react with other CD66 isoform
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ANC1D5
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Formulation
    Liquid
  • Gene ID1088
  • Target name
    CEACAM8
  • Target description
    CEA cell adhesion molecule 8
  • Target synonyms
    carcinoembryonic antigen CGM6; carcinoembryonic antigen gene family member 6; carcinoembryonic antigen related cell adhesion molecule 8; carcinoembryonic antigen-related cell adhesion molecule 8; CD66b; CD67; CD67 antigen; CGM6; NCA-95; non-specific cross-reacting antigen NCA-95
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP31997
  • Protein Name
    Carcinoembryonic antigen-related cell adhesion molecule 8
  • Scientific Description
    Human CD66b (CEACAM8, CGMb, NCA-95, CD67) is a 95kD member of the Carcinoembryonic Antigen (CEA) group. It is expressed on granulocytes and functions as an adhesion molecule. Similar to the CD66 a, c, and d isoforms, engagement of CD66b on neutrophils causes increased adhesion to endothelial cells. Crosslinking CD66b on neutrophils with antibodies triggers IL-8 release. - Monoclonal Antibody. Binds to CD66b on the cell surface of human PMN in flow cytometry and detects recombinant human CD66b in sandwich EIA utilizing either clone ANC4A4(Cat #ANC-220-020) or ANC3C5(Cat# ANC-219-020) as a capture reagent. May cross-react with other CD66 isoforms, as it also binds to the cell surface of an epithelial tumor line. Applications: ELISA, FACS. Isotype: Mouse IgG1kappa. Clone: ANC1D5. Liquid. 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. Human CD66b (CEACAM8, CGMb, NCA-95, CD67) is a 95kD member of the Carcinoembryonic Antigen (CEA) group. It is expressed on granulocytes and functions as an adhesion molecule. Similar to the CD66 a, c, and d isoforms, engagement of CD66b on neutrophils causes increased adhesion to endothelial cells. Crosslinking CD66b on neutrophils with antibodies triggers IL-8 release.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203