Anti-CD70 [BU69]

Absolute Antibody

Anti-CD70 [BU69]

7

BU69 has been used for FACS and immunocytochemistry analysis of the cell-surface expression levels of CD70 in renal cell carcinomas (Adam et al, 2006). It was shown in this study that cell-surface binding of BU69 to CD70 caused rapid internalisation of the cell-surface glycoprotein.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry

FACS; IHC; IP

Research Use Only

Monoclonal

BU69

CD70

CD70 molecule

CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A, CD70 antigen, CD27 ligand, Ki-24 antigen, surface antigen CD70, tumor necrosis factor ligand 8A, tumor necrosis factor ligand superfamily member 7

Mouse

IgG1

CD70 antigen

Human

Murine antibodies were produced by immunising BALB/c mice using the Waldenstrom's macroglobulinaemia cell line WM-1. Hybridomas were generated by fusion of immunised cells with the myeloma cell line P3/NS1/1-Ag4.1 via established methods.

-20°C,2°C to 8°C

12352203