Anti-CD8 alpha Rabbit mAb

PTM BIO

Anti-CD8 alpha Rabbit mAb

5

Flow Cytometry, ImmunoHistoChemistry Paraffin

IHC-P, FC

Research Use Only

Monoclonal

JRMR-10564-56

Unconjugated

Rabbit

IgG

T-cell surface glycoprotein CD8 alpha chain

CD8a is an integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, CD8a serves primarily as a coreceptor for MHC class I molecule: peptide complex and its function are involved with lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs). In NK-cells, the presence of CD8a homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8a homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203