Anti-CD80 Antibody [8-E5]

HUABIO

Anti-CD80 Antibody [8-E5]

7

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,FC

Research Use Only

Monoclonal

8-E5

2 mg/ml

Unconjugated

CD80

CD80 molecule

B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, T-lymphocyte activation antigen CD80, B-lymphocyte activation antigen B7, CD80 antigen (CD28 antigen ligand 1, B7-1 antigen), CTLA-4 counter-receptor B7.1, activation B7-1 antigen, costimulatory factor CD80, costimulatory molecule variant IgV-CD80

Mouse

IgG2b

T-lymphocyte activation antigen CD80

CD80/B7-1 is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of B7 to CD28 greatly upregulates the production of multiple lymphokines. B7-1 is a costimulatory molecule for the activation of both CD4+ and CD8+ T lymphocytes that prevents the induction of clonal anergy. Thus, the transfer of B7-1 genes into tumor cells can induce protective immunity and lead to tumor rejection of some tumors in model systems of in vivo tumor growth.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161