Anti-CD86 Mouse mAb

PTM BIO

Anti-CD86 Mouse mAb

5

Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry

ICC/IF, FC

Antibody

Research Use Only

Monoclonal

13053

Unconjugated

Mouse

IgG

T-lymphocyte activation antigen CD86

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG1 produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via Phosphorylatedlipase C and protein kinase C activation.

Stable for 12 months from date of receipt/reconstitution.

Human

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203