Anti-CD99 Antibody [PD00-13]

HUABIO

Anti-CD99 Antibody [PD00-13]

2

ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

PD00-13

1 mg/ml

Unconjugated

CD99

CD99 molecule (Xg blood group)

HBA71, MIC2, MIC2X, MIC2Y, MSK5X, CD99 antigen, E2 antigen, MIC2 (monoclonal antibody 12E7), T-cell surface glycoprotein E2, antigen identified by monoclonal 12E7, Y homolog, antigen identified by monoclonal antibodies 12E7, F21 and O13, cell surface antigen 12E7, cell surface antigen HBA-71, cell surface antigen O13, surface antigen MIC2

Rabbit

IgG

CD99 antigen

CD99 is a transmembrane glycoprotein, also known as MIC2, involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. It is involved in T-cell adhesion, leukocyte migration and differentiation of primitive neuroectodermal cell. CD99 labels lymphocyte, ovarian granulosa cells, pancreatic islet cells, Sertoli cells, CNS ependymal cells and endothelial cells. CD99 has been useful in diagnosis of Ewings sarcoma, sex cord-stromal tumor, endocrine tumor of pancreas. Additionally, it is found in a subset of other tumors including lymphoblastic lymphoma, breast carcinoma and other malignancies.

-20°C,2°C to 8°C

41116161