Anti-Cdc27 Antibody [SD85-02]

HUABIO

Anti-Cdc27 Antibody [SD85-02]

7

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P

Research Use Only

Monoclonal

SD85-02

1 mg/ml

Unconjugated

CDC27

cell division cycle 27

ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, H-NUC, HNUC, NUC2, cell division cycle protein 27 homolog, D0S1430E, D17S978E, anaphase promoting complex subunit 3, anaphase-promoting complex, protein 3, cell division cycle 27 homolog, nuc2 homolog

Rabbit

IgG

Cell division cycle protein 27 homolog

Cell division cycle protein 27 homolog is a protein that in humans is encoded by the CDC27 gene. The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.

Human

Human

Mouse,Rat

-20°C,2°C to 8°C

41116161