Anti-CDC5L Antibody [JJ091-05]

HUABIO

Anti-CDC5L Antibody [JJ091-05]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P

Research Use Only

Monoclonal

JJ091-05

1 mg/ml

Unconjugated

CDC5L

cell division cycle 5 like

CDC5, CDC5-LIKE, CEF1, PCDC5RP, dJ319D22.1, cell division cycle 5-like protein, CDC5 cell division cycle 5-like, Cdc5-related protein, dJ319D22.1 (CDC5-like protein), pombe cdc5-related protein

Rabbit

IgG

Cell division cycle 5-like protein

Cdc5L (Cell division cycle 5-like protein, Pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains 2 HTH myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. CDC5L is a spliceosomal protein that is highly conserved across species. It is a member of a protein group that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3 splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation with USF-2.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161