Anti-CDK1 Alexa Fluor(r) 488

EXBIO

Anti-CDK1 Alexa Fluor(r) 488

7

Immunocytochemistry: Recommended dilution 2 microg/ml; intracellular staining

ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

POH-1

0.1 mg/ml

AlexaFluor 488

IgG2a

Cdk1 (cyclin-dependent kinase 1), also known as p34Cdc2 (cell division control protein kinase 2) depends on cyclin A and B and is triggered by a positive feedback loop at the end of G2 phase, which is the key event that initiates mitotic entry. Destruction of cyclin B during metaphase results in inactivation of Cdk1, allowing mitotic exit and cell division. Cdk1 also contributes to the control of DNA replication. Cdk1 can be ihibited by several transcriptional targets of p53, such as p21WAF.

Bovine, Drosophila, Human, Mouse, Primate, Rat, Xenopus

2°C to 8°C

12352203