Anti-CEA [BW431/26]

Absolute Antibody

Anti-CEA [BW431/26]

9

This antibody recognizes and binds human carcinoembryonic antigen in its purified state as well as on tissue sections.

Technetium 99-labeled (Tc-99m) BW431/26 has been used in the diagnosis and detection of colorectal carcinomas, breast cancers, bladder carcinomas, lung adenocarcinomas and their recurrences by immunoscintigraphy (PMID: 2602902, 2662074, 2685692, 2297747, 2157833, 2166552, 2383485, 1984945 ). The use of Tc-99m-BW 431/26 immunoconjugates in immunoscintigraphy resulted in reduction of radiation dose for the patient down to 5% of the dose applied as compared with I-131 labelled MAbs (PMID: 3262953). Humanized version of this antibody also shows similar binding affinity as compared to its murine parent antibody (PMID: 1762576).

Research Use Only

Monoclonal

BW431/26

CEACAM5

CEA cell adhesion molecule 5

carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; meconium antigen 100

Mouse

IgG3

Carcinoembryonic antigen-related cell adhesion molecule 5

Human

-20°C,2°C to 8°C

12352203