Anti-CHD3 Antibody [JE57-05]

HUABIO

Anti-CHD3 Antibody [JE57-05]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,FC

Research Use Only

Monoclonal

JE57-05

1 mg/ml

Unconjugated

CHD3

chromodomain helicase DNA binding protein 3

Mi-2a, Mi2-ALPHA, SNIBCPS, ZFH, chromodomain-helicase-DNA-binding protein 3, ATP-dependent helicase CHD3, CHD-3, hZFH, mi-2 autoantigen 240 kDa protein, zinc finger helicase, zinc-finger helicase (Snf2-like)

Rabbit

IgG

Chromodomain-helicase-DNA-binding protein 3

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Human

Human

-20°C,2°C to 8°C

41116161