Anti-Ciguatoxin CTX3C [10C9]

Absolute Antibody

Anti-Ciguatoxin CTX3C [10C9]

7

This antibody specifically recognizes the ABCDE ring portion of ciguatoxin CTX3C and 51-OH-CTX3C. This antibody does not cross react with other toxins like brevetoxin A (BTX-A), brevetoxin B (BTX-B), okadaic acid (OA), and maitotoxin (MTX). Ciguatoxins ar

This antibody can be used to detect ciguatoxins in a sample using ELISA. It was also used in the development of a sandwich ELISA to detect CTX3C at the ppb level. Dissociation constant of this antibody for ciguatoxin CTX3C was Kd = 2.8 nM (PMID: 12812503). This antibody was also used in combination with another antibody 3D11 for effective neutralization of ciguatoxins in vitro and in vivo (PMID: 19254735).

ELISA, Neutralisation/Blocking

ELISA; neutralize

Research Use Only

Monoclonal

10C9

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Other Species

Species independent

The original antibody was generated by immunizing mice with a synthetic hapten comprising ABCDE ring portion conjugated with KLH.

-20°C,2°C to 8°C

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