Anti-Cip4 Antibody [JE63-45]
HA721029
ApplicationsWestern Blot
Product group Antibodies
TargetTRIP10
Overview
- SupplierHUABIO
- Product NameAnti-Cip4 Antibody [JE63-45]
- Delivery Days Customer2
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJE63-45
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9322
- Target nameTRIP10
- Target descriptionthyroid hormone receptor interactor 10
- Target synonymsCIP4, HSTP, STOT, STP, TRIP-10, cdc42-interacting protein 4, TR-interacting protein 10, protein Felic, salt tolerant protein, salt tolerator, thyroid receptor-interacting protein 10
- HostRabbit
- IsotypeIgG
- Protein IDP97531
- Protein NameCdc42-interacting protein 4
- Scientific DescriptionRequired for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161