Anti-Cisplatin modified DNA [CP9/19]

Absolute Antibody

Anti-Cisplatin modified DNA [CP9/19]

9

Antibody CP9/19 recognises only the intra-strand cross-links formed by cisplatin between adjacent purines.

This antibody binds to cisplatin-modified DNA and enables the quantification of cisplatin-induced adducts on DNA (Tilby et al., 1991; PMID: 1703029). This antibody has also been used for the isolation of DNA fragments carrying adducts to enhance the sensitivity of subsequent PCR-based analyses and is central to ongoing studies of variation in the nature of cisplatin adducts formed in different cell lines (McGurk et al., 2001; PMID: 11494859). This antibody has been used for IHC on mouse samples (Rainey et al., 2016; PMID: 27122034). This antibody was used in an IF assay to detect platinum-DNA adducts (Nicholson et al., 2022; PMID: 35778553).

Dot Blot, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

CP9/19

Rat

IgG2a

Other Species

-20°C,2°C to 8°C

12352203