Anti-Citrate Synthase Mouse mAb

PTM BIO

Anti-Citrate Synthase Mouse mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

WB, IHC-P, ICC/IF

Research Use Only

Monoclonal

JMMR-3604

Unconjugated

Mouse

IgG

Citrate synthase, mitochondrial

Citrate synthase (CS) is a mitochondrial enzyme that catalyzes the first and rate-limiting reaction of the citric acid cycle. The enzyme is responsible for the conversion of oxaloacetate and acetyl-CoA to citrate and CoA. Research studies show that CS knockdown HeLa cells are more malignant than vector-transfected cells from an in vivo xenograft model, which suggests a direct link between the Warburg Effect and tumor growth. Intervertebral disc degeneration, a growing health problem, has been linked to changes in citrate synthase activity.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203