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Anti-Cleaved PARP1 p25 Rabbit mAb

PTM-5272
PTM BIO
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
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Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-Cleaved PARP1 p25 Rabbit mAb
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin
  • Applications Supplier
    WB, IHC-P, ICC/IF
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    JRMR-243
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP09874
  • Protein Name
    Poly [ADP-ribose] polymerase 1
  • Scientific Description
    Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of glutamate and aspartate residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity Supplier
    Human, Mouse
  • Reactivity Supplier Note
    Protein A purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203

References

  • Meigui Zhang, et al. '(2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells' CHEMISTRY & BIODIVERSITY (2023)
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