Anti-Cn2 toxin [6009F]

Absolute Antibody

Anti-Cn2 toxin [6009F]

9

The binding specificity and characterization of this antibody towards Cn2 toxin of scorpion Centruroicles noxius was tested using ELISA. The epitope mapping of this antibody was performed using competitive ELISA. The scFv version of this antibody binds Cn2 toxin with an affinity of 410pM and capable of neutralizing 2 LD50 of Cn2 toxin when a 1 : 10 molar ratio of toxin-to-antibody fragment was used. It was also able to neutralize 2 LD50 of the whole venom (PMID: 15885107; US7381802). ELISA was also used to determine the cross- reactivity of this antibody towards other toxins like Cn3, Css2, and Css4 (PMID: 21156801).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

6009F

Beta-mammal toxin Cn2

Other Species

-20°C,2°C to 8°C

41116161