anti-Collagen IX antibody

Arigo Biolaboratories

anti-Collagen IX antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

COL9A1

collagen type IX alpha 1 chain

DJ149L1.1.2, EDM6, MED, STL4, collagen alpha-1(IX) chain, alpha-1(IX) collagen chain, cartilage-specific short collagen, collagen IX, alpha-1 polypeptide, collagen, type IX, alpha 1

Rabbit

IgG

This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

-20°C

12352203