Anti-Covid-19 & SARS-CoV Nucleocapsid [1C7C7]

Absolute Antibody

Anti-Covid-19 & SARS-CoV Nucleocapsid [1C7C7]

7

The antibody 1C7C7 detects SARS-CoV-2 and SARS-CoV-1 and can be used in affinity binding assays, flow cytometry, immunocytochemistry, and western blotting. Its effectiveness in detecting the nucleocapsid of the novel coronavirus causing COVID-19 was confirmed in multiple studies. For instance, it was used to analyze SARS-CoV-2 nucleoprotein extracted from infected cells via Western blot (Hoagland et al., 2020) ,and similarly by Blanco-Melo et al. in a study on imbalanced host response to SARS-CoV-2 (2020; pmid: 32416070). Another group has used this clone to stain infected cells fixed with 10% neutral formalin during a neutralization assay (Piepenbrink et al., 2020). Daniloski et al. performed similar staining procedure with 1C7C7 for a trans-complementation assay (2020; pmid: 33147445). Finally, this antibody was also used to stain SARs-CoV-2 infected cells in a study on in vitro susceptibility to SARS-CoV-2 infection (Dobrindt et al., 2020; pmid: 32995783).

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry

ELISA; IHC; FC; WB

Research Use Only

Nucleoprotein

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203