Anti-CRCP Antibody [JE65-42]

HUABIO

Anti-CRCP Antibody [JE65-42]

2

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE65-42

1 mg/ml

Unconjugated

Crcp

calcitonin gene-related peptide-receptor component protein

DNA-directed RNA polymerase III subunit RPC9, CGRP-RCP, CGRP-receptor component protein, CGRPRCP, RNA polymerase III subunit C9

Rabbit

IgG

DNA-directed RNA polymerase III subunit RPC9

This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway (By similarity).

-20°C,2°C to 8°C

41116161