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anti-Crf2 (Aspergillus fumigatus), mAb (rec.) (MS112-IIA1)

Research Use Only
AG-27B-6318
AdipoGen Life Sciences
ApplicationsELISA, Functional Assay, ImmunoFluorescence, ImmunoHistoChemistry, Western Blot
Product group Antibodies
ReactivityFungus
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-Crf2 (Aspergillus fumigatus), mAb (rec.) (MS112-IIA1)
  • Delivery Days Customer
    10
  • Applications
    ELISA, Functional Assay, ImmunoFluorescence, ImmunoHistoChemistry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MS112-IIA1
  • Concentration
    1 mg/ml
  • Estimated Purity
    >95%
  • Host
    Human
  • Isotype
    IgG1
  • Scientific Description
    Aspergillus fumigatus is a common airborne fungal pathogen for humans. It frequently causes an invasive aspergillosis (IA) in immunocompromised patients with poor prognosis. Potent antifungal drugs are very expensive and cause serious adverse effects. Their correct application requires an early and specific diagnosis of IA. Encoded by CRF1 gene, the Crf protein family contains three protein variants: Crf2 protein, amino acids (333 aa) long, Asp f9 protein (292 aa), first identified as an allergen using serum from Aspergillus-allergic patients and Crf1 (395 aa, also named Crh5). The glycosyol hydrolase/glycosidase Crf2 catalyzes the hydrolysis of glycosidic bonds in complex sugars and is located in the cell wall of the growing hyphae. Crf2 may be involved in the remodeling of the cell wall as well, and therefore in the growth and the virulence of the fungus. - Recombinant Antibody. Recognizes Crf2 from Aspergillus fumigatus. Possible cross-reactivity with Crf1, Crf2 and Asp f9 [Reference 2]. Applications: ELISA, FUNC, IHC, WB, IF. Clone: MS112-IIA1. Isotype: Human IgG1. Formulation: Liquid. In PBS. Aspergillus fumigatus is a common airborne fungal pathogen for humans. It frequently causes an invasive aspergillosis (IA) in immunocompromised patients with poor prognosis. Potent antifungal drugs are very expensive and cause serious adverse effects. Their correct application requires an early and specific diagnosis of IA. Encoded by CRF1 gene, the Crf protein family contains three protein variants: Crf2 protein, amino acids (333 aa) long, Asp f9 protein (292 aa), first identified as an allergen using serum from Aspergillus-allergic patients and Crf1 (395 aa, also named Crh5). The glycosyol hydrolase/glycosidase Crf2 catalyzes the hydrolysis of glycosidic bonds in complex sugars and is located in the cell wall of the growing hyphae. Crf2 may be involved in the remodeling of the cell wall as well, and therefore in the growth and the virulence of the fungus.
  • Reactivity
    Fungus
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203