Anti-Ctip2 Antibody [JF09-90]

HUABIO

Anti-Ctip2 Antibody [JF09-90]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,FC

Research Use Only

Monoclonal

JF09-90

1 mg/ml

Unconjugated

Bcl11b

B cell leukemia/lymphoma 11B

9130430L19Rik, B630002E05Rik, BCL-11B, Ctip2, Rit1, B-cell lymphoma/leukemia 11B, B-cell CLL/lymphoma 11B, B-cell lymphoma/leukaemia 11B, COUP-TF-interacting protein 2, mRit1, radiation-induced tumor suppressor gene 1 protein

Rabbit

IgG

B-cell lymphoma/leukemia 11B

Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161