Anti-Cytochrome C [E8]

Absolute Antibody

Anti-Cytochrome C [E8]

9

This antibody binds horse cytochrome c. This antibody recognizes three major discontiguous segments (33 to 39; 56 to 66; 96 to 104), and two minor sites on cyt c opposite to the exposed haem edge (PMID: 9698550).

The original mouse IgG1 version of this antibody binds horse cytochrome c with an affinity of Kd ~ 10(-9) M (PMID: 2993413). A solid phase radioimmunoassay was used to identify the specific epitope that the antibody binds (PMID: 2454225). The structural mechanism involved in the binding of the IgG1 antibody E8 to its highly charged protein antigen horse cytochrome c (cyt c) was studied using crystallographic structures (PMID: 9698550).

RadioImmunoAssay

Research Use Only

Monoclonal

E8

Mouse

IgG1

Cytochrome c

Equine

-20°C,2°C to 8°C

12352203