Anti-Cytokeratin 9 Antibody [SD201-09]

HUABIO

Anti-Cytokeratin 9 Antibody [SD201-09]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IF-Tissue,IF-Cell,IP

Research Use Only

Monoclonal

SD201-09

1 mg/ml

Unconjugated

KRT9

keratin 9

CK-9, EPPK, EPPK1, K9, keratin, type I cytoskeletal 9, cytokeratin 9, keratin 9, type I, type I cytoskeletal 9

Rabbit

IgG

Keratin, type I cytoskeletal 9

Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an alpha-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161