Anti-DCIR [9E8]

Absolute Antibody

Anti-DCIR [9E8]

9

This antibody is specific for human DCIR, which is expressed by monocytes, B cells, neutrophils, granulocytes and dendritic cells.

This antibody has been used in flow cytometric analysis of DCIR expression by peripheral blood mononuclear cells (Klechevsky et al, 2010). A recombinant humanised form of this antibody fused to protein antigens is under investigation as an antigen-targeting vaccine (Flamar et al, 2012), and has been shown to trigger antigen-specific CD8+ T cell immunity.

Flow Cytometry

Research Use Only

Monoclonal

9E8

CLEC4A

C-type lectin domain family 4 member A

CD367; CLECSF6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6; C-type lectin DDB27; C-type lectin domain family 4 member A; C-type lectin superfamily member 6; DCIR; DDB27; dendritic cell immunoreceptor; HDCGC13P; hDCIR; lectin-like immunoreceptor; LLIR

Human

IgG1

C-type lectin domain family 4 member A

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203