Anti DDX39 mAb (Clone 2E4)

Cosmo Bio USA

Anti DDX39 mAb (Clone 2E4)

16

Research Use Only

UniPlot Summary //Function: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. //Subcellular location: Nucleus. //Tissue specificity: Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland. //Sequence similarities: Belongs to the DEAD box helicase family. DECD subfamily. Contains 1 helicase ATP-binding domain. Reference 1. Pryor A., et al. Growth-regulatedexpressionand G0-specific turnover of the mRNA that encodes URH49, a mammalianDExH/D box protein that is highly related to the mRNA export protein UAP56. Nucleic Acids Res. 32:1857-1865(2004) 2. Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. 36:40-45(2004) 3. Sugiura T., et al. Intracellular characterization of DDX39, a novel growth-associated RNA helicase. Exp. Cell Res. 313:782-790(2007)

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