anti-Dengue virus NS1 antibody [SQab1503] (Biotin)
ARG65662
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityVirus
TargetPOLY
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Dengue virus NS1 antibody [SQab1503] (Biotin)
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSQab1503
- Concentration1 mg/ml
- ConjugateBiotin
- Gene ID1494449
- Target namePOLY
- Target descriptionpolyprotein
- Target synonymsDENV_gp1; polyprotein; polyprotein gene
- HostMouse
- IsotypeIgG
- Scientific DescriptionDengue virus NS1 protein is a nonstructural protein which could be secreted and have been developed as diagnostic biomarker for early detection. There are several forms of NS1 including monomer, dimer, and hexamer during infection. Dimeric NS1 can be anchored to cell membranes with glycosyl-phosphatidylinositol (GPI). Hexameric NS1 can be secreted and detected in patients blood samples (up to 50 microg/mL) or infected cell supernatants (various from ng/mL to microg/mL depend on serotypes and strains). Studies have shown that NS1 could interfere complement activity and prothrombin activation. In addition, NS1 could elicit antibodies which cross-react with host antigens including coagulation factors and molecules expressed in endothelial cells and platelets through molecular mimic.
- ReactivityVirus
- Storage Instruction-20°C
- UNSPSC12352203