Anti-Der p 2.0103 [7A1]

Absolute Antibody

Anti-Der p 2.0103 [7A1]

7

This antibody binds to an epitope on the Der p 2 which overlaps with the human IgE binding sites. The antibody recognized the six variants: Der p 2.0101, Der p 2.0102, Der p 2.0103, Der f 2.0101, Der f 2.0102, and Der f 2.0103.

The crystal structure of Der p 2.0103-7A1Fab was determined. The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody was able to inhibit Der p 2.0103 (Glesner et al., 2019; PMID: 31554696).

ELISA, Neutralisation/Blocking, Other Application

ELISA; inhibition; crystallography

Research Use Only

Monoclonal

7A1

Rabbit

IgG

Mite group 2 allergen Der p 2

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.

Other Species

Dermatophagoides pteronyssinus (European house dust mite)

The original antibody was isolated from a combinatorial phage display library generated from a mite allergic patient.

-20°C,2°C to 8°C

12352203