Anti-DNA [4B1]

Absolute Antibody

Anti-DNA [4B1]

9

This antibody is a polyspecific antibody that has binding specificity for ssDNA, actin, tubulin, cardiolipin and laminin.

This antibody is capable of binding ssDNA, actin, tubulin, cardiolipin and to laminin in a solid phase ELISA. Indirect immunofluorescence labeling of HEp-2 cells gave a cytoplasmic staining pattern similar to that obtained with anti-cytoskeleton antibodies. Western blot analysis demonstrated that mAb 4B1 bore idiotype D23, previously shown to be characteristic of natural antibodies derived from normal mice. This antibody was able to form glomerular immune deposits (Gilbert et al., 1995; PMID: 7540257).

ImmunoFluorescence, ELISA

Research Use Only

Monoclonal

4B1

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.

Other Species

-20°C,2°C to 8°C

12352203