Anti-DOPA Decarboxylase Antibody [JA53-16]
ET1704-94
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetDDC
Overview
- SupplierHUABIO
- Product NameAnti-DOPA Decarboxylase Antibody [JA53-16]
- Delivery Days Customer7
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJA53-16
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1644
- Target nameDDC
- Target descriptiondopa decarboxylase
- Target synonymsAADC, aromatic-L-amino-acid decarboxylase, dopa decarboxylase (aromatic L-amino acid decarboxylase)
- HostRabbit
- IsotypeIgG
- Protein IDO88533
- Protein NameAromatic-L-amino-acid decarboxylase
- Scientific DescriptionDOPA decarboxylase (DDC), also designated aromatic-L-amino-acid decarboxylase (AADC) belongs to the group II decarboxylase family of proteins. DDC, which can form a homodimer, is an important protein in the catecholamine biosynthesis pathway. DDC acts as a catalyst in the decarboxylation of L-5-hydroxytryptophan to serotonin, L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-tryptophan to tryptamine. Defects in the gene encoding for DDC may cause the autosomal recessive disorder AADC deficiency. AADC deficiency is an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency. This causes poor feeding, psychomotor and developmental delays, lethargy, ptosis, gastrointestinal disturbances and hypothermia.
- ReactivityHuman, Mouse
- Reactivity SupplierHuman,Mouse
- Reactivity Supplier NoteRat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161