Anti-Doublecortin Antibody [JJ0959]
ET1701-98
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDCX
Overview
- SupplierHUABIO
- Product NameAnti-Doublecortin Antibody [JJ0959]
- Delivery Days Customer7
- ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,FC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJJ0959
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1641
- Target nameDCX
- Target descriptiondoublecortin
- Target synonymsDBCN, DC, LISX, SCLH, XLIS, neuronal migration protein doublecortin, doublecortex, doublin, lis-X, lissencephalin-X
- HostRabbit
- IsotypeIgG
- Protein IDO43602
- Protein NameNeuronal migration protein doublecortin
- Scientific DescriptionLissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, resulting in severe mental retardation. Genetic analysis identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 shows sequence homology to beta-subunits of heterotrimeric G proteins. Doublecortin contains a consensus Abl phosphorylation site, and it has some sequence homology to a predicted kinase protein. Both proteins are highly expressed in developing brain, suggesting that they may be involved in a signal transduction pathway that is crucial to brain development.
- ReactivityHuman, Mouse, Rat
- Reactivity SupplierHuman,Mouse,Rat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161