Anti-Dynein Light Chain and recognizes rat and human homologs of both DYNLT1 and DNYLT3 [10F6-D1-D9]

Absolute Antibody

Anti-Dynein Light Chain and recognizes rat and human homologs of both DYNLT1 and DNYLT3 [10F6-D1-D9]

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This antibody is specific for DYNLT1 and DYNLT3 in both humans and rats. DYNLT1 and DYNLT3 act as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adap

To show the specificity of the mouse version of this antibody, immunoprecipitation and western blots on DYNLT1- and DYNLT3-GST fusion proteins were preformed with this antibody. Furthermore, the blotting and immunoprecipitating experiments were preformed on brain and tissue culture cell lysates and microtubule pellets prepared from rat brain. In both experiments it showed positive results. The antibody was isolated using ELISA on the DYNLT1- and DYNLT3-GST fusion proteins (Lo et al, 2007; pmid:17965411).

ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

Monoclonal

10F6-D1-D9

DYNLT3

dynein light chain Tctex-type 3

dynein light chain Tctex-type 3; protein 91/23; RP3; TCTE1L; TCTEX1L

Human

IgG1

Dynein light chain Tctex-type 3

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Rat

-20°C,2°C to 8°C

12352203