Anti-EAAT1 Antibody [JA30-35]

HUABIO

Anti-EAAT1 Antibody [JA30-35]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

WB,IHC-P

Research Use Only

Monoclonal

JA30-35

1 mg/ml

Unconjugated

SLC1A3

solute carrier family 1 member 3

EA6, EAAT1, GLAST, GLAST1, excitatory amino acid transporter 1, GLAST-1, glutamate/aspartate transporter 1, sodium-dependent glutamate/aspartate transporter 1, solute carrier family 1 (glial high affinity glutamate transporter), member 3

Rabbit

IgG

Excitatory amino acid transporter 1

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161