Anti-EDG2 Antibody [JE60-07]

HUABIO

Anti-EDG2 Antibody [JE60-07]

2

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE60-07

1 mg/ml

Unconjugated

LPAR1

lysophosphatidic acid receptor 1

EDG2, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1, lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2, lysophosphatidic acid receptor Edg-2, ventricular zone gene 1

Rabbit

IgG

Lysophosphatidic acid receptor 1

The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene. Plays a role in triggering inflammation in response to bacterial lipopolysaccharide (LPS) via its interaction with CD14. Promotes cell proliferation in response to lysophosphatidic acid. Required for normal skeleton development. May play a role in osteoblast differentiation. Required for normal brain development. Required for normal proliferation, survival and maturation of newly formed neurons in the adult dentate gyrus. Plays a role in pain perception and in the initiation of neuropathic pain

-20°C,2°C to 8°C

41116161